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Multiple sclerosis: Stem cell transplantation may halt disease progression

New research provides further evidence of autologous hematopoietic stem cell transplantation as an effective treatment for multiple sclerosis, after finding the procedure halted disease progression for 5 years in almost half of patients.   Lead study author Dr. Paolo Muraro, of the Department of Medicine at Imperial College London...

Early Results Show Irregular Heartbeat Improves After Mesenchymal Stem Cells Treatment

A new study published this month in STEM CELLS Translational Medicine indicates that treating heart patients with mesenchymal stem cells (MSCs) does not increase their risk of irregular heart beat (arrhythmia). In fact, the MSCs had the opposite effect and showed promise of improving the condition.   “This could...

Could Umbilical Cord Blood Banking Save Your Baby’s Life? Inside the Pregnancy Phenomenon

Of all the goods and services available to expectant parents, biological insurance—as blood cord banking is often considered—would seem a no-brainer. Yet it’s an incredibly expensive undertaking whose most intriguing benefits are linked to medical breakthroughs that we are still waiting for. The blood in a placenta and umbilical...

Stem cell transplants may induce long-term remission of multiple sclerosis

New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person’s own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS), an autoimmune disease in which the immune system attacks the central nervous system.   Five years after receiving the treatment,...

First-of-its-kind Study Explores if Stem Cells Might Lessen Inflammation in CF Patients

An Ohio cystic fibrosis (CF) patient was given an infusion of adult stem cells in a pioneering study that researchers hope will lead to therapies that reduce inflammation and infections linked to the disease.   “I am hoping the future generations of CF patients can get better treatments and...

Scientists Find Key Clues to Regulate Bone-Building Cells

The prospect of regenerating bone lost to cancer or trauma is a step closer to the clinic as University of Wisconsin-Madison scientists have identified two proteins found in bone marrow as key regulators of the master cells responsible for making new bone. In a study published online today (Feb....

HLA–identical sibling HSCT leads to high rate of 5-year survival in sickle cell disease

HLA–identical sibling transplantation showed promising long-term survival for children and adults with sickle cell disease, according to an international retrospective study. “Sickle cell disease and transplant physicians alike debate the burden of morbidity from a chronic disease and mortality from the disease, vs. the curative option with transplantation and...

Stem cell treatment may halt spread of multiple sclerosis

A treatment for multiple sclerosis that works by resetting the immune system appears to halt progression of the disease in almost half of patients and reverse the symptoms in some. A new study found the use of aggressive chemotherapy and a stem cell injection prevented symptoms from worsening for...

New Research Shows Stem Cell Therapy Improves Immune System and Overall Health In Older Individuals

The Interdisciplinary Stem Cell Institute at the University of Miami Miller School of Medicine (ISCI), today announced the results of new research using allogeneic human mesenchymal stem cells (hMSCs) for the treatment of frailty in older individuals. The results were presented as a late-breaking trial at the annual meeting...

Hematopoietic stem cell transplantation improved outcomes for patients with systemic scleroderma

WASHINGTON — Hematopoietic stem cell transplantation was associated with improvements in outcome compared to cyclophosphamide in patients with diffuse cutaneous systemic scleroderma, according to study results presented at the American College of Rheumatology Annual Meeting. Keith Sullivan, MD, of Duke University in Durham, N.C., and colleagues, randomly assigned 36...