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Parents of Two Children Diagnosed with Leukaemia Find Hope in Cord Blood

David Nassy, the father of two young children both diagnosed with acute lymphoblastic leukaemia (ALL) has described the devastation he and his partner, Marie-Anne, have suffered since their son’s diagnosis in January 2016 and their hope that cord blood stem cells from their newborn baby will offer a lifeline...

Could Umbilical Cord Blood Banking Save Your Baby’s Life? Inside the Pregnancy Phenomenon

Of all the goods and services available to expectant parents, biological insurance—as blood cord banking is often considered—would seem a no-brainer. Yet it’s an incredibly expensive undertaking whose most intriguing benefits are linked to medical breakthroughs that we are still waiting for. The blood in a placenta and umbilical...

Cord Blood Transplants Beneficial When Matched Donors Cannot Be Found

The majority of patients in need of allogeneic hematopoietic cell-transplants do not have HLA-matched donors available. Researchers recently performed a retrospective study including 582 patients with acute myeloid or lymphoid leukemia or myelodysplastic syndrome in need of hematopoietic cell-transplants. HLA-matched unrelated donors were found for 344 patients; 98 patients...

Cerebral palsy treatment with cord blood stem cells

Iranian researchers at Royan Institute are currently working on a project for testing umbilical cord blood stem cells as a potential treatment for cerebral palsy. Cerebral palsy, the most common physical disability in childhood, causes a wide range of physical symptoms, such as difficulties in walking and coordinating movements....

Bone marrow-derived stem cells offer blood transplant patients better quality of life

A large, nationwide study published in the journal JAMA Oncology found that people who received transplants of cells collected from a donor’s bone marrow the original source for blood stem cell transplants, developed decades ago had better self-reported psychological well-being, experienced fewer symptoms of a common post-transplant side effect called graft-vs.-host...

Researchers develop new strategy to limit side effects of stem cell transplants

Scientists in Germany have developed a new approach that may prevent leukemia and lymphoma patients from developing graft-versus-host disease (GvHD) after therapeutic bone marrow transplants. The researchers describe the successful application of their strategy in mice in “Exogenous TNFR2 activation protects from acute GvHD via host T reg cell...

Stem-cell transplants can boost immune system of blood cancer patients

As he vomited into the toilet after one of his bi-weekly chemotherapy sessions, Keith Oliver’s mom turned to him and asked him if he was still thankful. He glanced up at her. Are you serious? he thought. After being diagnosed with blood cancer, it was moments like this —...

Platelet production on large scale steps closer with new stem cell method

Researchers have taken a significant step toward the mass production of platelets for transfusion. They have found a way to create platelet-producing cells from stem cells faster and more efficiently than before. Platelets are small, colorless cell fragments whose main function is to interact with clotting proteins to stop...

RE-ENGINEERING STEM CELLS TO ERADICATE HIV IN LIFELONG SUFFERER

Aaron Kim has battled HIV since the moment he entered the world. Born three months premature in 1983, the second of twins, Aaron needed a blood transfusion to boost his red blood cell count. The nation’s blood supply wasn’t screened for HIV (human immunodeficiency virus) then because little was...

Bile acid supports the production of blood stem cells

Bile acid is transferred from the mother to the fetus via the placenta to enable the fetus to produce blood stem cells, new research shows. Bile acids are normally found in adults, to help digest food. However, in studies of pregnant mice, researchers found large amounts of bile acids...